Scandinavian Working Papers in Economics

IHE Report / IHE Rapport,
IHE - The Swedish Institute for Health Economics

No 2024:10: Compendium report on global challenges and opportunities to improve the care of women with triple-negative breast cancer

Andrea Manzano and Thomas Hofmarcher
Additional contact information
Andrea Manzano: IHE - The Swedish Institute for Health Economics
Thomas Hofmarcher: IHE - The Swedish Institute for Health Economics

Abstract: Breast cancer is a major global public health concern. One of the most aggressive and challenging subtypes of breast cancer is triple-negative breast cancer (TNBC). Around 10–20% of newly diagnosed cases breast cancer cases are TNBC, but because of its relatively low survival, TNBC accounts for around 30–40% of all breast cancer deaths. In contrast to other subtypes, innovations in the medical treatment of TNBC have been absent for many years. However, the recent introduction of immunotherapy and targeted therapy might be the beginning of a new era for TNBC patients.

This report provides a global perspective on TNBC. It primarily compiles key statistics, conclusions, and recommendations from earlier IHE reports on TNBC in the Asia-Pacific region, Europe/Northern America, and Latin America. It also adds information from a recent IHE report on breast cancer in the Middle East and Africa. The analysis of the care process is closely aligned with the three pillars of the WHO Global Breast Cancer Initiative. The report concludes with recommendations for policymakers to improve the quality of TNBC care.

Keywords: Breast cancer; TNBC; screening; medicines; immunotherapy; BRCA; Europe; Latin America; United States; Asia; Africa; Middle East

Language: English

41 pages, 2024

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